资 源 简 介
DiSCUS is a Python package designed to simulate bacterial growth and communication through horizontal gene transfer (conjugation). The software is based on a multi-agent methodology (thus, discrete) and uses the physics engine pymunk (www.pymunk.org) to support movements and collitions. The code allows the user to define intracellular machinery (gene regulatory networks) for general usage.
For more information regarding the construction of DiSCUS, its functioning and validation (along with a study of cell dynamics), please see:
DiSCUS documentation
An initial version of this software (without conjugation dynamics) was used to study the spatial behaviour of a genetic logic gate in:
Angel Goñi-Moreno and Martyn Amos. A reconfigurable NAND/NOR genetic logic gate. BMC Systems Biology 2012, 6:126 doi:10
