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Crann
Crann is the Irish word for "tree".
The program Crann has been developed in order to provide fast heuristic methods of detecting adaptive evolution in protein-coding genes. It is important that the user understands the advantages and limitations of these methods. It is also important for the user to know that the software is designed to perform a number of different tasks, however the interpretation of the results is left entirely to the user.
We strongly advise that every user familiarises themseleves with the Crann Manual and the original publications of the methods implemented in Crann.
References:
Creevey, C. and J. O. McInerney (2003). CRANN: Detecting adaptive evolution in protein-coding DNA sequences Bioinformatics 19: 1726. Link
Creevey, C. and J. O. McInerney (2002). An algorithm for detecting directional and non-directional
