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在使用成对的基因组BAC末端序列检测结构变化的源代码

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Rapid progress in comparative genomics among the grasses has revealed similar gene content and order despite exceptional differences in chromosome size and number. Large and small-scale genomic variations are of particular interest, especially among cultivated and wild species, since they encode rapidly evolving features that may be important in adaptation to particular environments. We present a genome-wide study of intermediate-sized structural variation (SV) among rice (O. sativa) and three of its closest relatives in the genus Oryza (O. nivara, O. rufipogon, and O. glaberrima). We computationally identified regional expansions, contractions, and inversions in the Oryza species genomes relative to O. sativa by combining data from paired-end clone alignments to the O. sativa reference genome and physical maps. The source code for this project from Hurwitz et al., The Plant Journal, 2010 is maintained here.

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